The facial appearance is fundamental in our social relations: it distinguishes and identifies us in our relationships with others. A tired and aged face, furrowed by wrinkles, is certainly less pleasant and less capable of achieving social success than a refreshed, harmonious and youthful one. The loss of volume in some areas of the face, such as the zygomatic region or the cheeks, and the skin aging are the main processes involved in facial aging. A number of treatments can restore harmony and freshness to the face: today it is possible not only to repair but also to regenerate your own face by using mesenchymal stem cells (ADSCs Adipose Derived Stem Cells) from your own adipose (fat) tissue, thanks to the new technique that Dr. Gennai standardized and published: S.E.F.F.I. (Superficial Enhanced Fluid Fat Injection) and MicroSEFFI.
It is a minimally invasive procedure which ensures natural and harmonious results, without any sacrifice of your social life. The SEFFI procedure (fat and stem cells ADSCs transfer) aims to restore volume and regenerate tissue achieving a natural, safe and long lasting result.
The SEFFI and MicroSEFFI procedure
Dr. Gennai’s team has been studying the use of stem cells for regenerative purposes since 2012; they standardized the SEFFI technique (Superficial Enhanced Fluid Fat Injection). This technique addresses the regeneration of tissues and the restoration of volumes in facial rejuvenation. This injecting procedure is safe, simple, effective and long lasting; at the base of this procedure is the volumizing effect of the adipocytes and the regenerating effect of the ADSCs. This technique has aroused such a great international interest that they had the opportunity and honor to publish it in 2015 in two of the most relevant international scientific journals i.e. the Aesthetic Surgery Journal and JAMA Facial Plastic Surgery.
In the meantime, they have been studying another procedure aimed to inject adipocytes and ADSCs in very delicate areas such as the periocular and perioral areas: we named this technique MicroSEFFI (Micro Superficial Enhanced Fluid Fat Injection). MicroSEFFI too aroused great international interest and has been published on ASJ in 2016.
In the last 30 years, the only surgical rejuvenation procedure has been the face lift which is aimed to tight the skin but not rejuvenate the face. Extremely interesting is a survey where 100 patients were compared with their pictures when they were 20 years old: this survey proved that the most important effect in the aging face is the loss of volume, followed by the skin aging and the descent of tissue holding the third place. Moreover, in my cases report of 500 facial rejuvenation procedures the average age of my patients is 45-50 years. In the light of this evidence, I am deeply convinced that in order to achieve a natural facial rejuvenation it is mandatory to RESTORE the volume, then REGENERATE the skin and next REPOSITION the tissue. This is the reason why my facial rejuvenation procedure is called R3 (cubed). The R3 procedure has been published on AMJ in 2016.
Regenerative therapy, thanks to the insertion of the stem cells present in the subcutaneous tissue (ADSCs) allows rejuvenating the tissue and restoring tone, turgidity and shine to the skin.
SEFFILLER offers the next level in aesthetics treatment. The procedure takes the regenerative benefits of stem cell rejuvenation with the immediate results of dermal fillers. Renowned aesthetics physician, Dr. Gary Merlino trained under Dr. Gennai, now offers this amazing treatment in South Florida.
The SEFFILLER® treatment is a unique medical treatment because it allows you to perform a true regenerative therapy with an outpatient treatment of a few minutes.
The sampling is extremely simple, and is performed with a microcannula in an area of the body where there is adipose tissue. The area is previously anesthetized with local anesthetic. The stem cell sample is then used in conjunction with dermal filler.
The effects of the treatment are noticed after 24 hours and the regenerating action reaches its maximum between 2 and 4 months. Depending on the patient’s skin condition, a cycle of 2-4 treatments can be recommended throughout the year.